Extraction-Free Protocols Delete The Purchase Entirely
Direct lysis approaches take a swab or a lysate straight into amplification, removing the extraction step and with it the kit sale. Roughly 14% of assays already run this way, mostly high-volume respiratory panels where sample quality is predictable and throughput matters more than yield. Sensitivity is genuinely lower on difficult samples, which limits how far it spreads. Assay developers pursue it anyway, because every deleted step removes cost, hands-on time and one more contamination opportunity. Every protocol that validates removes that volume permanently rather than moving it elsewhere entirely.
Market Impact: Handles 40 mL environmental samples








