Contract Manufacturers Became Gatekeepers After Liver Safety Scrutiny
Liver injury case reports involving concentrated catechin extracts put contract manufacturers in an uncomfortable position, since they carry production liability and reputational exposure if a brand they produce for is named in a report. They responded by tightening what material they would accept, requiring catechin profile documentation, residual solvent data and batch consistency records before formulating at all. That narrowed the supplier base considerably without any regulator instructing it. Roughly 58% of volume now moves as specified rather than commodity grade material. No regulator instructed any of it, which is the striking part.
Market Impact: Specifications typically sit at 50%








