Genome Mining Revives Interest in Overlooked Polyether Ionophores
Genome mining and machine learning tools now flag biosynthetic gene clusters for polyether ionophores in Streptomyces strains, which sends screening groups back to known but neglected compounds such as abierixin. Natural product screening libraries grow about 15% a year, and each new library adds demand for verified reference lots. The trend needs strain access, identity proof, and small-lot supply, and it rewards producers with well-characterised strains and clean analytical records. Batch records protect future sales. Cost control separates leaders from followers. Clear specifications build buyer trust. Small importers feel every input swing.
Market Impact: NIH budget near $47 billion








